How do you calculate the corrected WBC count given an uncorrected WBC count of 30,000/uL and 100 nucleated RBC in 100 WBC?

To calculate the corrected white blood cell (WBC) count when there are nucleated red blood cells (nRBCs) present, it's important to adjust the uncorrected WBC count based on the number of nRBCs.

In this scenario, you have an uncorrected WBC count of 30,000 cells per microliter (µL) and identified 100 nucleated red blood cells in 100 white blood cells. The formula for the corrected WBC count is:

Corrected WBC count = Uncorrected WBC count × (100 / (100 + nRBC count))

Given that there are 100 nRBCs, the calculation would look like this:

Corrected WBC count = 30,000 × (100 / (100 + 100))

Corrected WBC count = 30,000 × (100 / 200)

Corrected WBC count = 30,000 × 0.5

Corrected WBC count = 15,000 µL

Thus, the corrected WBC count is 15,000/uL, confirming the accuracy of the calculation and the correctness of the selected answer. This adjustment is crucial for clinical decision-making, as