At what temperature should fresh frozen plasma be stored?

Fresh frozen plasma should be stored at temperatures of -30°C or colder to maintain its quality and functionality. This storage condition prevents the degradation of clotting factors and other proteins present in the plasma, ensuring that it remains effective when transfused.

Maintaining such low temperatures helps in preserving the integrity of the components within the plasma. At these temperatures, the risk of microbial growth and chemical changes that could compromise the product is minimized.

Other temperature ranges, such as 0°C or colder, -18°C, or 2°C to 6°C, do not sufficiently inhibit the enzymatic activity and biological changes that can occur over time, which could lead to a reduced potency and efficacy of the plasma when it is eventually used for transfusions.