According to AABB guidelines, how long can thawed fresh frozen plasma be refrigerated before discard?

Thawed fresh frozen plasma (FFP) can be stored in the refrigerator for up to 24 hours before it must be discarded, according to AABB guidelines. This time frame is established to ensure the quality and safety of the plasma, as the components within the plasma can degrade over time, impacting its efficacy when transfused.

FFP is typically used in transfusion medicine to replace clotting factors and to manage coagulopathy. After thawing, if it's not used within this 24-hour window, the risk of bacterial growth and the deterioration of clotting factor levels increases, making the product less effective for patient management. Keeping these guidelines in mind ensures compliance with safety standards and promotes positive patient outcomes. Other time options like 12, 48, or 72 hours exceed this recommended period and would contravene patient safety protocols.